Synthesis of the ezomycin octosyl nucleoside

Article abstract of DOI:10.1021/jo00084a005

Efficient chain extension of β-D-galactopyranosyl cyanide, cyclization to a bicyclic octose, and then attachment of cytosine affords the ezomycinoctosyl nucleoside 17 in a form suitable for elaboration to the ezomycins (e.g., 1).