Copper-mediated alkylation of vitamin DC-ring. Synthesis of C11-functionalized 1α,25-dihydroxyvitamin D3

DOI: 10.1016/S0040-4020(97)00692-3

Source and publish data:

Tetrahedron p. 10851 - 10870 (1997)

Update date:2022-08-04

Topics:

Authors:

Torneiro, Mercedes

Fall, Yagamare

Castedo, Luis

Mourino, Antonio

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(97)00692-3

This work describes our studies on the functionalization at C11 of CD-ring fragments of vitamin D₃ using organocopper reagents. As an application, an efficient, convergent synthesis of 11α-[3,3-(dimethoxy)propyl] calcitriol analogue 2, which ma

Full text of DOI:10.1016/S0040-4020(97)00692-3

Products guided by the article

Product name:(1R,3S)-5-[2-[(1R,3aS,6S,7aR)-6-(3,3-Dimethoxy-propyl)-1-((R)-5-hydroxy-1,5-dimethyl-hexyl)-7a-methyl-octahydro-inden-(4E)-ylidene]-eth-(Z)-ylidene]-4-methylene-cyclohexane-1,3-diol

Cas No:139619-73-1

R&D Labs maybe for 139619-73-1

JiangXi Keyuan Biopharma Co., LTD.

Contact:+86-563-6833666

Address:Guangde Fine Chemical Zone, Anhui Province, China
Synchem Pharma Co.,Ltd(expird)

Contact:+0086-21-61984905-1

Address:Building 60,Zimian Park, LongYang industrial Area, 1515Nong，Yuandong Road Fengxian District, Shanghai ,China
Beijing Chemdow Co., Ltd

website:http://www.chemdow.com

Contact:0086-10-82435335

Address:Room 401,Unit 3,4th Floor,Shangdijiayuan,Shangdi East Road, Haidian District,Beijing
SHENZHEN PENGCHENG REDSTAR INDUSTRY CO.,LTD

Contact:+86-755-82412922

Address:Room 8066, East Block, Square City, Jiabin Road, Luohu District
Shandong Xinhua Pharmaceutical Co.,Ltd

website:http://www.xhzy.com

Contact:+86-533-2196801

Address:1 lutai road,zhangdian dis,Zibo City

Relevant to this article

Glycosylations of cyclopropyl-modified carbohydrates: Remarkable β-selectivity using a mannose building block

Doi:10.1021/ol3024133
(2012)
Ligand-Directed Approach to Activity-Based Sensing: Developing Palladacycle Fluorescent Probes That Enable Endogenous Carbon Monoxide Detection

Doi:10.1021/jacs.0c06405
(2020)
A new synthetic route for 1,2-diketo compounds using unexpected C-C bond cleavage by PCC

Doi:10.1016/j.tetlet.2012.07.095
(2012)
Chondroitin sulfate N-acetylgalactosaminyltransferase-1 (CSGalNAcT-1) involved in chondroitin sulfate initiation: Impact of sulfation on activity and specificity

Doi:10.1093/glycob/cwr172
(2012)
Rapid access to compound libraries through flow technology: Fully automated synthesis of a 3-aminoindolizine library via orthogonal diversification

Doi:10.1021/co300094n
(2012)
Design and synthesis of sarolaner, a novel, once-a-month, oral isoxazoline for the control of fleas and ticks on dogs

Doi:10.1016/j.bmcl.2016.02.027
(2016)

Article Doi