
Tetrahedron Letters p. 3821 - 3824 (1993)
Update date:2022-08-04
Topics:
Hardinger, Steven A.
Wijaya, Ngadi
A rapid and efficient method for the protection of primary and secondary alcohols as their tert-butyldiphenylsilyl (tBDPS) ethers was developed. Reaction of the alcohol and tBDPSCl in DMF with AgNO3, NH4NO3, or NH4ClO4 provides good yields of the corresponding silyl ethers.
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