Syntheses, resolution, and structure-activity relationships of potent acetylcholinesterase inhibitors: 8-Carbaphysostigmine analogues

Article abstract of DOI:10.1021/jm00086a011

The synthesis of a series of 1,2,3,3a,8,8a-hexahydroindeno[2,1-b]pyrrole 5-alkylcarbamates and their resolution are reported. These compounds are structurally related to physostigmine with substitution of a methylene group in place of the NMe group at pos