Conjugated addition of 2-bromomethyl-3-phenoxypropene zinc to methylenemalonic acid derivatives; further conversion to methylene-cyclopentanes

DOI: 10.1016/S0040-4039(00)93972-8

Source and publish data:

Tetrahedron Letters p. 475 - 476 (1992)

Update date:2022-07-29

Topics:

Authors:

Van der Heide

Van der Baan

Bickelhaupt

Klumpp Klumpp

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Article abstract of DOI:10.1016/S0040-4039(00)93972-8

Addition of the title zinc reagent to the C=C bond of methylenemalonic acid derivatives followed by aqueous work-up, deprotonation with NaH and Pd(O)-catalyzed cyclization leads to methylenecyclopentanes.

Full text of DOI:10.1016/S0040-4039(00)93972-8

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