Ring cleavage of 2-phenyl-3,5,6,7,8,8a-hexahydro-imidazo[1,2-a]pyridin-1-oxide by substitution

Article abstract of DOI:10.1002/ardp.19923250210

The cyclic α-amino nitrone 2 reacts with Grignard reagents yielding the ring opened 2-substituted piperidine oximes 7 and 8, but not the substituted cyclic hydroxylamines of type 4, a formerly supposed. The structures of 7 and 8 were proved by unequivocal