Tetrahedron Letters p. 667 - 670 (1992)
Update date:2022-07-29
Topics:
Cid
De March
Figueredo
Font
Milan
The 1,3-dipolar cycloaddition of 3,4,5,6-tetrahydropyridine 1-oxide, 1, to 2(5H)-furanones 2, 3, and 4 is investigated. Crucial nmr data are indicated to determine the conformational equilibria and stereochemistry of the adducts. The major products arise from exo transition states.
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Doi:10.1021/ol402325z
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