Chemo-enzymatic synthesis of Fmoc-peptide fragments

Article abstract of DOI:10.1080/00397919208055416

Optically pure Fmoc-peptide fragments have been prepared via dicyclohexylcarbodiimide coupling of N-protected amino acids with amino cid esters, followed by enzyme-catalyzed ester hydrolysis by alcalase with a high concentration of organic solvent in a hi

Full text of DOI:10.1080/00397919208055416

This article was downloaded by: [Carnegie Mellon University]
On: 13 January 2015, At: 00:24
Publisher: Taylor & Francis
Informa Ltd Registered in England and Wales Registered Number: 1072954
Registered office: Mortimer House, 37-41 Mortimer Street, London W1T 3JH,
UK
Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
Publication details, including instructions for
authors and subscription information:
http://www.tandfonline.com/loi/lsyc20
Chemo-Enzymatic Synthesis of
Fmoc-Peptide Fragments
Shui-Tein Chen a , Shu-Chyong Hsiao a , Chung-Ho
Chang a & Kung-Tsung Wang a
a Institute of Biological Chemistry , Academia Sinica,
P. O. Box 23—106, Taipei, Taiwan , 10098
Published online: 05 Dec 2006.
To cite this article: Shui-Tein Chen , Shu-Chyong Hsiao , Chung-Ho Chang & Kung-
Tsung Wang (1992) Chemo-Enzymatic Synthesis of Fmoc-Peptide Fragments, Synthetic
Communications: An International Journal for Rapid Communication of Synthetic
Organic Chemistry, 22:3, 391-398, DOI: 10.1080/00397919208055416
To link to this article: http://dx.doi.org/10.1080/00397919208055416
PLEASE SCROLL DOWN FOR ARTICLE
Taylor & Francis makes every effort to ensure the accuracy of all the
information (the “Content”) contained in the publications on our platform.
However, Taylor & Francis, our agents, and our licensors make no
representations or warranties whatsoever as to the accuracy, completeness,
or suitability for any purpose of the Content. Any opinions and views
expressed in this publication are the opinions and views of the authors, and
are not the views of or endorsed by Taylor & Francis. The accuracy of the
Content should not be relied upon and should be independently verified with
primary sources of information. Taylor and Francis shall not be liable for any
losses, actions, claims, proceedings, demands, costs, expenses, damages,
and other liabilities whatsoever or howsoever caused arising directly or

indirectly in connection with, in relation to or arising out of the use of the
Content.
This article may be used for research, teaching, and private study purposes.
Any substantial or systematic reproduction, redistribution, reselling, loan,
sub-licensing, systematic supply, or distribution in any form to anyone is
expressly forbidden. Terms & Conditions of access and use can be found at
http://www.tandfonline.com/page/terms-and-conditions