Development of selective inhibitors against plasma kallikrein

DOI: 10.1248/cpb.39.2930

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 2930 - 2936 (1991)

Update date:2022-07-29

Topics:

Authors:

Teno Teno

Wanaka Wanaka

Okada Okada

Tsuda Tsuda

Okamoto Okamoto

Hijikata-Okunomiya

Naito Naito

Okamoto Okamoto

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Article abstract of DOI:10.1248/cpb.39.2930

Specific plasma kallikrein inhibitors were designed and synthesized and their structure-activity relationship was studied. trans-4-Aminomethylcyclohexanecarbonyl(Tra)-lysyl-4-ethoxycarbonylanili de inhibited plasma kallikrein and plasmin with 1C_{50
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Full text of DOI:10.1248/cpb.39.2930

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