STUDIES ON SIALIC ACIDS I. DETERMINATION OF ANOMERIC CONFIGURATION OF NEURAMINIC ACID DERIVATIVES BY CIRCULAR DICHROISM

Article abstract of DOI:10.1016/S0040-4039(01)82928-2

CD spectra were recorded for methyl α- and β-glycosides of D-neuraminic acid, and the band at the wave-length lower than 200 nm was attributed to the acetamido group.The Cotton effect at higher wave-length around 220 nm arose from the n-?^* transition of the carboxyl group.Thus α-linked glycosides showed a negative band, while β-glycosides gave arise to a positive band.