Cholecystokinin dipeptoid antagonists: Design, synthesis, and anxiolytic profile of some novel CCK-A and CCK-B selective and 'mixed' CCK-A/CCK-B antagonists

DOI: 10.1021/jm00057a005

Source and publish data:

Journal of Medicinal Chemistry p. 552 - 565 (1993)

Update date:2022-09-26

Topics:

Authors:

Boden Boden

Higginbottom

Hill Hill

Horwell Horwell

Hughes Hughes

Rees Rees

Roberts Roberts

Singh Singh

Suman-Chauhan

Woodruff

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Article abstract of DOI:10.1021/jm00057a005

The design, synthesis, and structure-activity relationships (SAR) for the development of selective dipeptoid ligands for both of the cholecystokinin (CCK) receptor subtypes CCK-A and CCK-B are described. The SAR developed is used to design a ligand with e

Full text of DOI:10.1021/jm00057a005

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