Diastereoselective fluorination of chiral imide enolates using N-Fluoro-O-Benzenedisulfonimide (NFOBS)

DOI: 10.1016/S0040-4039(00)91883-5

Source and publish data:

Tetrahedron Letters p. 1153 - 1156 (1992)

Update date:2022-08-05

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Authors:

Davis, Franklin A.

Han, Wei

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Article abstract of DOI:10.1016/S0040-4039(00)91883-5

α-Fluoro acids (78-90% ee) and β-fluoro alcohols (89->95%ee) of well defined stereochemistry are prepared via the diastereoselective fluorination of chiral imide enolates with NFOBS (3).

Full text of DOI:10.1016/S0040-4039(00)91883-5

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