Stereospecific synthesis of 4-fluoroglutamic acids

DOI: 10.1016/S0040-4039(00)91661-7

Source and publish data:

Tetrahedron Letters p. 1509 - 1512 (1992)

Update date:2022-08-05

Topics:

Authors:

Avent Avent

Bowler Bowler

Doyle Doyle

Marchand

Young Young

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Article abstract of DOI:10.1016/S0040-4039(00)91661-7

A stereospecific route to 4-fluoroglutamic acids from pyroglutamic acid has been devised and variable temperature ¹H-nmr spectroscopic studies have explained apparent inconsistencies in the stereochemical outcome of steps in a synthesis of 4-fluoroglutamic acids from hydroxyprolines.

Full text of DOI:10.1016/S0040-4039(00)91661-7

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