Synthesis and anti-HIV-1 activity of 4,5,6,7-tetrahydro-5- methylimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-one (TIBO) derivatives. 4

DOI: 10.1021/jm00005a006

Source and publish data:

Journal of Medicinal Chemistry p. 794 - 802 (1995)

Update date:2022-08-03

Topics:

Authors:

Kukla Kukla

Breslin Breslin

Ludovici

Grous Grous

Diamond Diamond

Miranda Miranda

Rodgers Rodgers

De Clercq

Pauwels Pauwels

Andries Andries

Janssen Janssen

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Article abstract of DOI:10.1021/jm00005a006

In previous papers, we have described the discovery of a new series of compounds, 4,5,6,7-tetrahydro-5-methylimidazo[4,5,1-jk][1,4]benzodiazepin- 2(1H)-ones, TIBO (1 and 1a), with potent anti-HIV-1 activity and the synthesis of analogues to better define

Full text of DOI:10.1021/jm00005a006

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