Palladium-catalyzed reduction of an allylic amine: A formal access to both diastereoisomers of cyclopentenyl glycine

Article abstract of DOI:10.1016/S0040-4039(00)91600-9

The easily accessible bicyclic amines 3 (exo or endo) are regioselectively transformed to the methyl esters of the diastereoisomers (1c or 1d) of N-benzyl cyclopentenylglycine by reaction with hydride donors (mainly NaBH₃CN) in the presence of