Synthesis and angiotensin II receptor antagonist activity of C-linked pyrimidine derivatives

DOI: 10.1016/0223-5234(96)88246-8

Source and publish data:

European Journal of Medicinal Chemistry p. 365 - 376 (1995)

Update date:2022-09-26

Topics:

Authors:

Nicolai, E.

Cure, G.

Goyard, J.

Kirchner, M.

Teulon, J. M.

et al. et al.

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Article abstract of DOI:10.1016/0223-5234(96)88246-8

The synthesis and pharmacological activity of nonpeptide angiotensin II (Ang II) receptor antagonists are presented.These 3-N-substituted pyrimidine 4(3H)-one and 4-O,N,S-substituted pyrimidine derivatives represent a series of C-linked biphenyl tetrazole

Full text of DOI:10.1016/0223-5234(96)88246-8

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Product name:4'-[2-Methyl-4-(2-methylsulfanyl-ethoxy)-6-propyl-pyrimidin-5-ylmethyl]-biphenyl-2-carbonitrile

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