Tetrahedron Letters p. 1725 - 1728 (1992)
Update date:2022-08-04
Topics:
Dhanoa, Daljit S.
Parsons, William H.
Greenlee, William J.
Patchett, Arthur A.
An efficient synthesis of a novel class of potent macrocylic renin inhibitors exemplified by compounds 1 and 2, which involves the marcocyclization of 8 and 9 as the key step, is described. The macrocyclic design of renin inhibitors 1 and 2 disclosed here
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Doi:10.1021/acs.orglett.7b00999
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(2012)Doi:10.1002/ejoc.201200730
(2012)Doi:10.1021/acs.joc.5b02705
(2016)Doi:10.1016/0223-5234(92)90061-5
(1992)Doi:10.1016/j.tet.2012.10.034
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