Molecules p. 8762 - 8772 (2012)
Update date:2022-08-04
Topics:
Sorra, Kumaraswamy
Chang, Chi-Fen
Pusuluri, Srinivas
Mukkanti, Khagga
Laiu, Min-Chiau
Bao, Bo-Ying
Su, Chia-Hao
Chuang, Ta-Hsien
A series of amido-substituted triazolopyrrolo[2,1-c][1,4]benzodiazepine (PBDT) derivatives was synthesized from isatoic anhydride, and their cytotoxicity against the MRC-5 and Mahlavu cell lines was evaluated. The results suggest that compound PBDT-7i with the meta-trifluoromethylbenzoyl substituent can selectively inhibit the growth of Mahlavu cells and has low toxicity towards MRC-5 cells.
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Doi:10.1055/s-0032-1316613
(2012)Doi:10.1039/c4ra02092h
(2014)Doi:10.1021/ol302904c
(2012)Doi:10.1039/c9cc06151g
(2019)Doi:10.1016/j.tet.2012.10.059
(2013)Doi:10.1016/j.jfluchem.2012.07.010
(2012)