Journal of Medicinal Chemistry p. 2002 - 2006 (1992)
Update date:2022-08-03
Topics:
Singh, Shyam K.
Singer, Sara C.
Ferone, Robert
Waters, Kathleen A.
Mullin, Robert J.
Hynes, John B.
A novel folic acid analogue, Nα-(5-deaza-5,6,7,8-tetrahydropteroyl)-L-ornithine, 3, was prepared via a multistep synthetic sequence.The key steps involved the conversion of 5-deazapteroic acid to its N10-formyl derivative followed by
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