Highly Diastereoselective Reduction and Addition of Nucleophiles to Binaphthol-protected Arylglyoxals

DOI: 10.1016/S0957-4166(00)80276-1

Source and publish data:

Tetrahedron Asymmetry p. 365 - 366 (1992)

Update date:2022-07-29

Topics:

Authors:

Maglioli, Paola

Lucchi, Ottorino De

Delogu, Giovanna

Valle, Giovanni

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Article abstract of DOI:10.1016/S0957-4166(00)80276-1

Arylglyoxals, protected at the aldehyde function with 1,1'-binaphthalene-2,2'-diol, are readily prepared by direct nucleophilic substitution of binaphthol-sodium salt on dibromoacetophenone and react highly diastereoselectively with lithium aluminium hydr

Full text of DOI:10.1016/S0957-4166(00)80276-1

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