Triplex Formation of an Oligonucleotide Containing 2'-O-Methylpseudoisocytidine with a DNA Duplex at Neutral pH

DOI: 10.1021/jo00037a048

Source and publish data:

Journal of Organic Chemistry p. 3225 - 3230 (1992)

Update date:2022-08-02

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Authors:

Ono, Akira

Ts'o, Paul O. P.

Kan, Lou-sing

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Article abstract of DOI:10.1021/jo00037a048

The synthesis of the hexadecanucleotide 5'TTTT1TTTT111111T3' (1-16mer) containing 2-amino-5-(2-O-methyl-β-D-ribofuranosyl-4(1H)-pyrimidinone (2'-O-methylpseudoisocytidine or 1) is described.Triplex formation of 1-16mer with a deoxyribonucleotide duplex 5'

Full text of DOI:10.1021/jo00037a048

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Product name:N²-<(dimethylamino)methylene>-2'-O-methyl-5'-O-(dimethoxytrityl)pseudoisocytidine

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