Diels-Alder Cycloadditions Using Nucleophilic 3-(p-Tolylthio)-2-pyrone. Regiocontrolled and Stereocontrolled Synthesis of Unsaturated, Bridged, Bicyclic Lactones

DOI: 10.1021/jo00041a009

Source and publish data:

Journal of Organic Chemistry p. 4083 - 4088 (1992)

Update date:2022-08-05

Topics:

Authors:

Posner, Gary H.

Nelson, Todd D.

Kinter, Chris M.

Johnson, Neil

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00041a009

Captodative 3-(tolylthio)-2-pyrone (1) is shown to be reactive as a nucleophilic diene undergoing 2 + 4-cycloadditions with various electrophilic alkenes under sufficiently mild thermal conditions ( View More

Full text of DOI:10.1021/jo00041a009

Products guided by the article

Product name:methyl 4-(4'-methylbenzenesulfenyl)-3-oxo-2-oxabicyclo<2.2.2>oct-7-ene-5-exo-methyl-5-endo-carboxylate

Cas No:141510-36-3

R&D Labs maybe for 141510-36-3

Dalian Join King Biochemical Tech. Co., Ltd.

Contact:0411 39216206

Address:814 First State Blvd
Nowa pharmaceuticals Co., LTD

Contact:86-512-69362780,69362785

Address:No.69 Weixin Road,Weiting Town,Suzhou Industrial Park
JiangXi Hong Run Chemical Co., Ltd

Contact:+86-0791-88521351

Address:XingHuo industrial zone in YongXiu county
GUANGZHOU MEDCAN PHARMATECH LTD

website:http://www.gzmedcan.com

Contact:+86-20-82519649

Address:Building J,Room 101,1 JiangtashanRd,Guang Zhou Science City,Guang Zhou ,China
Chiral Quest (Suzhou) Company Ltd

website:http://www.chiralquest.com

Contact:+86-0512-62956066

Address:B1/9, 218 Xinghu Street, Suzhou Industrial Park

Relevant to this article

Application of Suzuki arylation, Sonogashira ethynylation and Rosenmund-von Braun cyanation in the exploration of substitution effects on the anticancer activity of 2-aroylquinolines

Doi:10.1039/c2ob26614h
(2012)
Triarylimidazole redox catalysts: Electrochemical analysis and empirical correlations

Doi:10.1021/jo302309m
(2013)
Host (aluminum incorporated mesocellulous silica foam (Al-MCF))-guest (tungsten polyoxometalate) nanocomposite material: An efficient and reusable catalyst for selective oxidation of sulfides to sulfoxides and sulfones

Doi:10.1016/j.catcom.2012.09.018
(2012)
Oxidative dimerization of (hetero)aromatic amines utilizing t-BuOI leading to (hetero)aromatic azo compounds: Scope and mechanistic studies

Doi:10.1021/jo402120w
(2013)
Imidazopyridine-based inhibitors of glycogen synthase kinase 3: Synthesis and evaluation of amide isostere replacements of the carboxamide scaffold

Doi:10.1002/cbdv.201200308
(2012)
Cobalt(II)-mediated synthesis of 2,6-bis[5,7-di-tert-butyl-1,3-benzoxazol- 2-yl]-pyridine: Structural analysis and coordination behavior

Doi:10.1016/j.molstruc.2012.09.078
(2013)

Article Doi