Journal of the American Chemical Society p. 58 - 61 (2013)
Update date:2022-08-05
Topics: N-heterocyclic carbene β-lactones
Candish, Lisa
Lupton, David W.
The N-heterocyclic carbene (NHC)-catalyzed Claisen rearrangement of hybrid Ireland-Coates structures has been achieved, allowing the stereoselective synthesis of highly functionalized β-lactones. The reaction proceeds with high diastereoselectivity (>20:1
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