Tetrahedron p. 2739 - 2760 (1992)
Update date:2022-08-04
Topics:
De Kimpe
De Cock
Stevens
The synthesis of N-(1-halo-2-alkylidene)amines, i.e. α-halomethyl ketimines, is described for the first time, utilizing the TiCl4-induced condensation of α-halomethyl ketones with primary amines. The reactivity of these new α-halomethylketimines was studied with respect to nucleophiles such as iodide, cyanide, alcohols, alkoxides, amines and thiolates. α-Halomethyl ketimines are powerful ambident electrophiles which underwent a variety of reactions leading to functionalized imines and heterocycles.
View MoreNingbo Distant Chemicals Co.,Ltd
Contact:86-574-27862490,27862438
Address:5F-3,#54 DaShaNi street,Ningbo,CHINA
VanderArk International Limited
Contact:86-10-82437576
Address:Qing He
HANGZHOU PANYU CHEMICAL CO.,LIMITED
Contact:+86-571-86578491
Address:Rm 605, NO.1870 Binsheng Road,Binjiang Dist, Hangzhou, China
Shaanxi King Stone Enterprise Company Limited
Contact:86-29-88353805,13609285751
Address:.209 Keji Road Hi-Tech industrial Develpment Zone .Xian China
Weifang Ocean Trading Co., Ltd.
Contact:+86-536-2081155
Address:Room2606, Yuqing Building, 518#, Yuquan Road, High-tech Development Zone, Weifang City, Shandong Province, China
Doi:10.1016/S0040-4039(00)85100-X
(1986)Doi:10.1021/ja01308a049
(1935)Doi:10.1016/j.molcatb.2013.06.016
(2013)Doi:10.1021/om00043a076
(1992)Doi:10.1039/c2dt32487c
(2013)Doi:10.1021/acs.orglett.0c02378
(2020)
