4-O-benzyl-2,3-O-isopropylidene-D-erythrose and -D-threose from 2,3-O-isopropylidene-D-glyceraldehyde via thiazole intermediates. Synthesis of 2-deoxykanosamine

Article abstract of DOI:10.1055/s-1992-34166

The adduct derived from 2,3-O-isopropylidene-D-glyceraldehyde and 2-(trimethylsilyl)thiazole is readily converted into the title D-erythrose (50% overal yield) by selective protection of the hydroxy groups and cleavage of the thiazole ring; the D-threose