Preparation of C-4 alkylated dideoxyribosides: Potential precursors to a novel series of nucleosides

Article abstract of DOI:10.1055/s-1992-34158

Methallyl alcohol can be converted in five simple operations (alkylation, epoxidation, alkynyl-coupling, hydroboration/oxidation, cyclization) to C-5 protected, chiral, non-racemic dideoxyribosides containing an alkyl appendage at the C-4 site.