A convenient one-pot synthesis of an unsymmetrical propane-1,3-diamine BRL 61010A

Article abstract of DOI:10.1080/00397919908086040

The one-pot condensation of N-methylhomoveratrylamine with acrolein followed by in situ reductive amination with 3,4-dimethoxyaniline to give an unsymmetrical propane 1,3-diamine in excellent yield is described.

Full text of DOI:10.1080/00397919908086040

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Synthetic Communications: An
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A convenient One-Pot
Synthesis of an Unsymmetrical
Propane-1,3-diamine BRL
61010A
Robin P Attrill a , Thomas W Ramsay a , Graham R
Slater a & Paul Smith a
a Synthetic Chemistry SmithKline Beecham
Pharmaceuticals, New Frontiers Science Park, Third
Avenue , Harlow, Essex, CM19 5AW
Published online: 17 Sep 2007.
To cite this article: Robin P Attrill , Thomas W Ramsay , Graham R Slater & Paul
Smith (1999) A convenient One-Pot Synthesis of an Unsymmetrical Propane-1,3-
diamine BRL 61010A, Synthetic Communications: An International Journal for
Rapid Communication of Synthetic Organic Chemistry, 29:5, 827-833, DOI:
10.1080/00397919908086040
To link to this article: http://dx.doi.org/10.1080/00397919908086040
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