4,5-Dihydro-1-phenyl-1H-2,4-benzodiazepines: Novel Antiarrhythmic Agents

DOI: 10.1021/jm00074a017

Source and publish data:

Journal of Medicinal Chemistry p. 3361 - 3370 (1993)

Update date:2022-08-04

Topics: Novel Antiarrhythmic Agents Experimental

Authors:

Johnson, Robert E.

Baizman, Eugene R.

Becker, Carolyn

Bohnet, Eric A.

Bell, Rebecca H.

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00074a017

A series of 4,5-dihydro-1-phenyl-1H-2,4-benzodiazepines has been identified as potential antiarrhythmic agents that interact with sodium and potassium channels and prolong the ventricular effective refractory period (ERP) in anesthetized guinea pigs.Conco

Full text of DOI:10.1021/jm00074a017

Products guided by the article

Product name:1H-2,4-Benzodiazepine, 3-(chloromethyl)-4,5-dihydro-4-methyl-1-phenyl-

Cas No:142150-28-5

R&D Labs maybe for 142150-28-5

Shenzhen HwaGen Pharmaceutical Co., Ltd

website:http://www.rafflespt.com

Contact:+86-752-5538396

Address:Guangdong Huizhou China
Shanghai Sungo Technology Chemical Co., Ltd

Contact:0086-21-51385579

Address:Room2010, F/20, Tonghua Plaza, NO 345 Jinxiang Road, Jinqiao Export Processing Zone, Shanghai, 201206 P.R.CHINA
jiangsu senxuan pharmaceutical and chemical co.,ltd

Contact:86-523-87982810

Address:hongqiao industrial zone,taixing,jiangsu china
Nantong LiKai Chemical Co.,Ltd

Contact:+86-513-89068669

Address:Jincheng Science Park
Ningbo J&S Botanics Inc.

Contact:86-574-26865651

Address:529 YuanBaoShan Road, Beilun District

Relevant to this article

Synthesis of π-conjugated 2,2:6′,2″-terpyridine-substituted oligomers based on 3,4-ethylenedioxythiophene

Doi:10.1021/ol303512f
(2013)
Catalytic hydrotrifluoromethylation of unactivated alkenes

Doi:10.1021/ja401022x
(2013)
Nonpeptide angiotensin II receptor antagonists. 1. Synthesis and in vitro structure-activity relationships of 4[[[(1H-pyrrol-1- ylacetyl)amino]phenyl]methyl]imidazole derivatives as angiotensin II receptor antagonists

Doi:10.1021/jm00064a007
(1993)
Gold-catalyzed addition of N-hydroxy heterocycles to alkynes and subsequent 3,3-sigmatropic rearrangement

Doi:10.1021/ol4000789
(2013)
Multisubstituted benzo[b]furans through a copper- and/or palladium-catalyzed assembly and functionalization process

Doi:10.1016/j.tet.2012.12.058
(2013)
Tuning photovoltaic performance of 9,9-dioctylfluorene-alt-5,7- bis(thiophen-2-yl)-2,3-biphenylthieno[3,4-b]pyrazine copolymeric derivatives by attaching additional donor units in pendant phenyl ring

Doi:10.1002/pola.26284
(2012)

Article Doi