4,5-Dihydro-1-phenyl-1H-2,4-benzodiazepines: Novel Antiarrhythmic Agents

DOI: 10.1021/jm00074a017

Source and publish data:

Journal of Medicinal Chemistry p. 3361 - 3370 (1993)

Update date:2022-08-04

Topics: Novel Antiarrhythmic Agents Experimental

Authors:

Johnson, Robert E.

Baizman, Eugene R.

Becker, Carolyn

Bohnet, Eric A.

Bell, Rebecca H.

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00074a017

A series of 4,5-dihydro-1-phenyl-1H-2,4-benzodiazepines has been identified as potential antiarrhythmic agents that interact with sodium and potassium channels and prolong the ventricular effective refractory period (ERP) in anesthetized guinea pigs.Conco

Full text of DOI:10.1021/jm00074a017

Products guided by the article

Product name:1H-2,4-Benzodiazepine, 3-(chloromethyl)-4,5-dihydro-4-methyl-1-phenyl-

Cas No:142150-28-5

R&D Labs maybe for 142150-28-5

jiangsu hualin chemical co.,ltd.

Contact:86-25-87787402

Address:jaingsu,china
Xi'an caijing Opto-Electrical Science & Technology Co., LTD

Contact:+86-29-88294447

Address:NO.168 Zhangba Rd. East, Xi'an, P.R.China
CHANGZHOU HANGYU PHARMACEUTICAL TECHNOLOGY CO., LTD

website:http://www.czyys.com

Contact:0086-519-88802789

Address:No.300,Yanling Middle Road, Changzhou, Jiangsu, China
Nanjing Chemipioneer Pharma&Tech Co.,Ltd

website:http://www.chemipioneer.com.cn

Contact:+86-25-52685700

Address:Room 305，A Block，Biological-Medicine Building，Business Start-up Center，Xin-ke 1st Road, High-tech development zone，Nanjing city，Jiangsu Province, China
Jiangxi Dongxu Chemical Science & Technology Co.,Ltd

Contact:+86-791-86899381

Address:Nanchang, Jiangxi, China

Relevant to this article

Synthesis of π-conjugated 2,2:6′,2″-terpyridine-substituted oligomers based on 3,4-ethylenedioxythiophene

Doi:10.1021/ol303512f
(2013)
Catalytic hydrotrifluoromethylation of unactivated alkenes

Doi:10.1021/ja401022x
(2013)
Nonpeptide angiotensin II receptor antagonists. 1. Synthesis and in vitro structure-activity relationships of 4[[[(1H-pyrrol-1- ylacetyl)amino]phenyl]methyl]imidazole derivatives as angiotensin II receptor antagonists

Doi:10.1021/jm00064a007
(1993)
Gold-catalyzed addition of N-hydroxy heterocycles to alkynes and subsequent 3,3-sigmatropic rearrangement

Doi:10.1021/ol4000789
(2013)
Multisubstituted benzo[b]furans through a copper- and/or palladium-catalyzed assembly and functionalization process

Doi:10.1016/j.tet.2012.12.058
(2013)
Tuning photovoltaic performance of 9,9-dioctylfluorene-alt-5,7- bis(thiophen-2-yl)-2,3-biphenylthieno[3,4-b]pyrazine copolymeric derivatives by attaching additional donor units in pendant phenyl ring

Doi:10.1002/pola.26284
(2012)

Article Doi