Nonpeptide angiotensin II receptor antagonists. 1. Synthesis and in vitro structure-activity relationships of 4[[[(1H-pyrrol-1- ylacetyl)amino]phenyl]methyl]imidazole derivatives as angiotensin II receptor antagonists

DOI: 10.1021/jm00064a007

Source and publish data:

Journal of Medicinal Chemistry p. 1735 - 1745 (1993)

Update date:2022-08-04

Topics: Synthesis In vitro Structure-activity relationships Nonpeptide angiotensin II receptor antagonists

Authors:

Sircar Sircar

Winters Winters

Quin III

Major Major

Panek Panek

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Article abstract of DOI:10.1021/jm00064a007

A novel series of non-biphenylyltetrazole angiotensin II receptor antagonists which contain a 1H-pyrrol-1-ylacetyl residue in place of the benzoyl residue in EXP 6803 have been developed. The receptor binding activity of several members of this new series

Full text of DOI:10.1021/jm00064a007

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