Inhibition of N8-acetylspermidine deacetylase by active-site-directed metal coordinating inhibitors.

DOI: 10.1021/jm00091a009

Source and publish data:

Journal of medicinal chemistry p. 2414 - 2418 (1992)

Update date:2022-08-04

Topics:

Authors:

Huang Huang

Dredar Dredar

Manneh Manneh

Blankenship

Fries Fries

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00091a009

A number of substrate analogues of N8-acetylspermidine (N8-AcSpd) (16) and chemical modifying agents containing metal coordinating ligands were assayed as inhibitors of the cytoplasmic enzyme N8-AcSpd deacetylase from rat liver. The enzyme is inhibited by

Full text of DOI:10.1021/jm00091a009

Products guided by the article

Product name:2-Oxa-3,10,14-triazapentadecan-15-oic acid, 10-[(1,1-dimethylethoxy)carbonyl]-4-oxo-1-phenyl-, 1,1-dimethylethyl ester

Cas No:142160-54-1

R&D Labs maybe for 142160-54-1

shanghai payne pharm co.,ltd.

Contact:+86-021-58123769

Address:No.780 of Cailun Road,Zhangjiang Hi-tech Park,Pudong,Shanghai
hangzhou sunchem trading co., ltd.

Contact:13588470430--

Address:Room 406-407, the 4th Building, No549
Nanjing Vincero International Trading Co.,Ltd

Contact:8618936897229

Address:NO.68, ZhuShan Road, JiangNing WanDa Plaza, Building E Room 1703
NOVASYNCS CO., LTD

Contact:0512-63006287

Address:no.88.YISHENG Road,etdz-WUJIANG,SUZHOU,CHINA
XZL BIO-TECHNOLOGY CO., LTD.

Contact:0086 533 2282832

Address:Zibo，Shandong

Relevant to this article

Facile access to bis(indolyl)methanes by copper-catalysed alkylation of indoles using alcohols under air

Doi:10.1016/j.tetlet.2021.152936
(2021)
Rhodium-catalyzed synthesis of 2,3-diaryl-1,4-diketones via oxidative coupling of benzyl ketones using α-thioketone oxidizing reagent

Doi:10.1016/j.tetlet.2012.12.107
(2013)
1-(5'-Fluoro-6'-hydroxy-5',6'-dihydrouracil-5'-yl)-5-fluorouracil, a novel N(1)-C(5)-linked dimer that releases 5-fluorouracil by radiation activation under hypoxic conditions [1]

Doi:10.1021/jm00092a023
(1992)
NNN-Ruthenium Catalysts for the Synthesis of Pyridines, Quinolines, and Pyrroles by Acceptorless Dehydrogenative Condensation

Doi:10.1021/acs.organomet.8b00359
(2018)
Adenosine dioxolane nucleoside phosphoramidates as antiviral agents for human immunodeficiency and hepatitis B viruses

Doi:10.1021/ml4001497
(2013)
Ligations of N-acyl tryptophan units to give native peptides via 7-, 10-, 11- and 12-membered cyclic transition states

Doi:10.1039/c3ob27421g
(2013)

Article Doi