New total synthesis of bikaverin

DOI: 10.1016/S0040-4039(00)78863-0

Source and publish data:

Tetrahedron Letters p. 2805 - 2806 (1992)

Update date:2022-08-03

Topics:

Authors:

Bekaert, Alain

Andrieux, Jean

Plat, Michel

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Article abstract of DOI:10.1016/S0040-4039(00)78863-0

On the basis of non-catalysed thermal condensation of a Mannich based with a phenol, followed by dehydration to an o.quinonic chromene further isomerized to a p.quinonic one, the synthesis of bikaverin 7 has been achieved via a six-step route involving selective dealkylation of bikaverin-dimethylether 6.

Full text of DOI:10.1016/S0040-4039(00)78863-0

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