Asymmetric synthesis XVII. New chiral catalysts for the stereocontrolled addition of benzaldehyde by diethylzinc

Article abstract of DOI:10.1016/0957-4166(92)80023-P

Enantioselective addition of benzaldehyde with diethylzinc catalyzed by a few classes of new chiral ligands (3a-3h) and their structural relations are disclosed herein. The stereocontrolled syntheses of both (S)- and (R)-1-phenyl-1-propanol are achieved i