Macrocyclic polyether tetralactams I: Synthesis and cyclization studies

DOI: 10.1016/S0040-4020(01)80444-0

Source and publish data:

Tetrahedron p. 4347 - 4358 (1992)

Update date:2022-08-04

Topics:

Authors:

Duriez Duriez

Pigot Pigot

Picard Picard

Cazaux Cazaux

Tisnes Tisnes

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Article abstract of DOI:10.1016/S0040-4020(01)80444-0

A three-step method for the synthesis of new 18,21 or 24-membered macrocyclic tetralactams with two dimethyleneoxy moieties is described. The method consists in the ring closure of a bis-secondary amine with a diamide diacid derivative activated by the th

Full text of DOI:10.1016/S0040-4020(01)80444-0

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