Total Synthesis of (+)-9,10-syn- and (+)-9,10-anti-Copalol via Epoxy Trienylsilane Cyclizations

DOI: 10.1021/jo00043a014

Source and publish data:

Journal of Organic Chemistry p. 4598 - 4608 (1992)

Update date:2022-07-30

Topics:

Authors:

Yee, Nathan K. N.

Coates, Robert M.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00043a014

Total syntheses of (+)-9,10-syn-copalol (5), the pyrophosphate ester of which is a likely intermediate in the biosynthesis of 9,10-syn diterpenes, and its 9,10-anti isomer 39 are reported.Lithiation of (-)-(6R)-6,7-epoxygeranyl p-tolylsulfone (-)-19 or (+

Full text of DOI:10.1021/jo00043a014

Products guided by the article

Product name:2,6-Octadienoic acid, 6-methyl-8-(phenylmethoxy)-2-[(trimethylsilyl)methyl]-, ethyl ester, (E,E)-

Cas No:142720-30-7

R&D Labs maybe for 142720-30-7

Allicon Pharmaceuticals,Inc.

Contact:+86-519-86339586，13584329896

Address:Changzhou Scientific and Education Park
Guangxi Shanyun Biochemical Science and Technology Co., Ltd

Contact:+86-0772--6828887

Address:#2 Industrial Park of Luzhai County, Liuzhou, Guangxi, China
Chemsky（shanghai）International Co.,Ltd.

Contact:0

Address:0
Zhenjiang Huayu I/E Co.,LTD

Contact:86-511-85210668 0511-85210668, 85210818, 85210898

Address:Yihai Garden E-902,NO.99 Daxi RD., Zhenjiang Jiiangsu ,China
Puyang Huicheng Electronic Material Co., Ltd

website:http://huichengchem.weba.testwebsite.cn/index_en.html

Contact:+86-393-8910800

Address:West Section Shengli Road, Puyang457000, China

Relevant to this article

Synthesis of Di- and Triarylmethanes through Palladium-Catalyzed Reductive Coupling of N -Tosylhydrazones and Aryl Bromides

Doi:10.1055/s-0036-1588893
(2017)
1-(Benzenesulfonyl)- and 1-(p-Toluenesulfonyl)-3-methylimidazolium Triflates: Efficient Reagents for the Preparation of Arylsulfonamides and Arylsulfonates

Doi:10.1021/jo00043a046
(1992)
Structure activity relationships of human galactokinase inhibitors

Doi:10.1016/j.bmcl.2014.11.061
(2015)
Facile one pot multicomponent synthesis of novel 4-(benzofuran-2-yl)-2-(3-(aryl/heteryl)-5-(aryl/heteryl)-4,5-dihydro-1H-pyrazol-1yl)thiazole derivatives

Doi:10.1080/00397911.2018.1440600
(2018)
Chemistry and pharmacological studies of 3-alkoxy-2,5-disubstituted- pyridinyl compounds as novel selective α4β2 nicotinic acetylcholine receptor ligands that reduce alcohol intake in rats

Doi:10.1021/jm4000374
(2013)
Synthesis, characterization and hplc analysis of the (1S,2S,5R)-diastereomer and the enantiomer of the clinical candidate ar-15512

Doi:10.3390/molecules26040906
(2021)

Article Doi