Total Synthesis of (+)-9,10-syn- and (+)-9,10-anti-Copalol via Epoxy Trienylsilane Cyclizations

Article abstract of DOI:10.1021/jo00043a014

Total syntheses of (+)-9,10-syn-copalol (5), the pyrophosphate ester of which is a likely intermediate in the biosynthesis of 9,10-syn diterpenes, and its 9,10-anti isomer 39 are reported.Lithiation of (-)-(6R)-6,7-epoxygeranyl p-tolylsulfone (-)-19 or (+