Synthesis of 3-episiastatin B analogues having anti-influenza virus activity

DOI: 10.7164/antibiotics.46.1883

Source and publish data:

Journal of Antibiotics p. 1883 - 1889 (1993)

Update date:2022-09-26

Topics:

Authors:

Nishimura

Umezawa Umezawa

Kondo Kondo

Takeuchi

Mori Mori

Kijima-Suda

Tomita Tomita

Sugawara

Nakamura

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Article abstract of DOI:10.7164/antibiotics.46.1883

Two epimers of siastatin B, 3-episiastatin B and 3,4-diepisiastatin B, were obtained by the chemical modification of siastatin B. Compound 3 showed marked inhibitory activity against influenza virus neuraminidases and significant inhibition of influenza v

Full text of DOI:10.7164/antibiotics.46.1883

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Product name:N-(tert-butoxycarbonyl)-3,4-didehydro-4-deoxysiastatin B benzyl ester

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