Journal of Medicinal Chemistry p. 3648 - 3652 (1992)
Update date:2022-08-03
Topics:
Lee, Melinda J. C.
Nagasawa, Herbert T.
Elberling, James A.
DeMaster, Eugene G.
In the preceding paper, analogs of chlorpropamide with an OMe substituent on the sulfonamide nitrogen were shown to inhibit aldehyde dehydrogenase (AlDH), and it was postulated that these compounds were bioactivated by O-demethylation to release nitroxyl
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