Journal of Organic Chemistry p. 5328 - 5334 (1992)
Update date:2022-08-04
Topics:
Hermann, Christine K. F.
Campbell, James A.
Greenwood, Thomas D.
Lewis, Judith A.
Wolfe, James F.
N-Acyl-2-chlorobenzenesulfonamides 7a-d undergo competitive metal-halogen exchange and ortho-deprotonation or α-deprotonation reactions when treated sequentially with sodium hydride and n-butyllithium.The o-lithio intermediates derived from metal-halogen
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