Thiophene Systems. 14. Synthesis and Antihypertensive Activity of Novel 7-(Cyclic amido)-6-hydroxythienopyrans and Related Compounds as New Potassium Channel Activators

DOI: 10.1021/jm00101a020

Source and publish data:

Journal of Medicinal Chemistry p. 4425 - 4433 (1992)

Update date:2022-08-04

Topics:

Authors:

Sanfilippo, Pauline J.

McNally, James J.

Press, Jeffery B.

Fitzpatrick, Louis J.

Urbanski, Maud J.

et al. et al.

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Article abstract of DOI:10.1021/jm00101a020

The synthesis and antihypertensive activity of novel 7-(cyclic amido)-6-hydroxy-5,5-dimethylthieno<3,2-b>pyrans and related compounds are described.The compounds were tested for oral antihypertensive activity in spontaneously hypertensive rats (SHR) and s

Full text of DOI:10.1021/jm00101a020

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