Tetrahedron Letters p. 3567 - 3570 (1992)
Update date:2022-08-04
Topics:
Chan, Ming Fai
Hsiao, Chi-Nung
(2S,3R,4S)-2-Amino-1-cyclohexyl-6-methylheptane-3,4-diol, a dihydroxyethylene dipeptide isostere for renin inhibitors, was synthesized from D-ribose stereospecifically.This method can be readily adapted to other dihydroxyethylene isosteres.
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