Improved ruthenium-catalyzed amination of alcohols with ammonia: Synthesis of diamines and amino esters

Article abstract of DOI:10.1002/anie.201103199

Diamination of diols: The first homogeneously catalyzed diaminations of primary and secondary diols with ammonia give the corresponding diamines. Other primary as well as secondary alcohols including hydroxy-substituted esters can also be efficiently converted to primary amines. This atom-efficient and selective amination method proceeds in an ammonia atmosphere without additional hydrogen sources. Copyright