Michael-additions of 6-aminopyrimidin-4-ones to enones: Semi-empirical MO calculations and experimental investigations

DOI: 10.1002/ardp.19923250607

Source and publish data:

Archiv der Pharmazie p. 341 - 348 (1992)

Update date:2022-08-05

Topics: Enones

Authors:

Troschutz

Anders Anders

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Article abstract of DOI:10.1002/ardp.19923250607

AM1- and PM3 calculations reveal a satisfactory correlation between the charge densities at the C-5 atom (q(C-5), Table 2) of compounds 1, 2, 4a-c and their enamine-like nucleophilicity towards enones 3 and 9. Furthermore, in this series the similarity of

Full text of DOI:10.1002/ardp.19923250607

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