Syntheses of a glycerophospholipid, C16-platelet activating factor and a palmitoyl analogue of M-5, an anti-inflammatory glyceroglycolipid

DOI: 10.1248/cpb.40.1166

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1166 - 1169 (1992)

Update date:2022-08-04

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Authors:

Shibuya Shibuya

Kawashima

Narita Narita

Kitagawa

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Article abstract of DOI:10.1248/cpb.40.1166

From a chiral C4-epoxide (-)-3, which is one of the synthons in our synthetic strategy for complex lipids, a glycerophospholipid C16-platelet activating factor (C16-PAF, 1) and a palmitoyl analogue (2) of an anti-inflammatory glyceroglycolipid M-5, which was previously isolated from the Okinawan marine sponge Phyllospongia foliascens, have been synthesized.

Full text of DOI:10.1248/cpb.40.1166

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