Practical synthesis of T-3761, (S)-10-(1-aminocyclopropyl)-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyr ido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid

DOI: 10.1248/cpb.42.2629

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 2629 - 2632 (1994)

Update date:2022-08-04

Topics:

Authors:

Todo Todo

Takagi Takagi

Iino Iino

Hayashi Hayashi

Takata Takata

Kuroda Kuroda

Momonoi Momonoi

Narita Narita

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Article abstract of DOI:10.1248/cpb.42.2629

An economical 11-step synthesis of T-3761 (1), a new quinolone antibacterial agent discovered by us, has been developed. Commercially available 2,3,4,5-tetrafluorobenzoic acid (2) has been transformed to 4-(1-acetaminocyclopropyl)-2,3,5-trifluorobenzoic a

Full text of DOI:10.1248/cpb.42.2629

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Product name:Benzoic acid, 4-(1-aminocyclopropyl)-2,3,5-trifluoro-

Cas No:143785-86-8

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Zhengzhou Institute of Chiral Pharmer Research Co., Ltd.

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Hangzhou Dingyan Chem Co., Ltd

website:http://www.dingyanchem.com

Contact:86-571-87157530

Address:RM.1118,NO.1 Building, Baiyun Tower,Jianggan Area, Hangzhou city, China,310004
Zhejiang Quzhou Jiancheng Silicone Co., Ltd.(Shanghai Jiancheng Industial and Trade Co, Ltd)

Contact:18957018777 +86-570-3888777

Address:The company production base address： Quzhou City, Zhejiang Province high-tech industrial park Nianhua Road 37
AUSHUN PHARMACEUTICAL TECHNOLOGY CO,.LTD

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Address:14 Dayingbi, Zhujiang Rd. East, Nanjing, Jiangsu, China.
Hubei Lingsheng Pharmaceuticals Co., Ltd.

Contact:+86-0710-3538058

Address:Xiangyang City Xiangcheng Economic Development Zone, Hubei Province

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