Lewis-acid-induced reactions of α-methoxyglycinamide derivatives with silyl enol ethers. Formation of 3-amino-2-pyrrolidines and 3-amino-2-pyrrolinones

Article abstract of DOI:10.1002/recl.19921110705

In order to develop an expedient synthetic route to γ-oxo-α-aminocarboxamides, five different α-(alkoxycarbonyl)amino-α-methoxyacetamides were subjected to borontrifluoride-etherate-mediated reactions with one silyl ketene acetal and four silyl enol ether