Thromboxane Receptor Antagonism Combined with Thromboxane Synthase Inhibition. 3. Pyridinylalkyl-Substituted 8-octanoic Acids

Article abstract of DOI:10.1021/jm00101a014

A series of 8-<(arylsulfonyl)amino>octanoic acids substituted with a pyridinylalkyl group along the chain were synthesized and tested in vitro for their ability to both antagonize the binding of thromboxane A₂ to its receptors and to inhibit th