Thromboxane Receptor Antagonism Combined with Thromboxane Synthase Inhibition. 3. Pyridinylalkyl-Substituted 8-octanoic Acids

DOI: 10.1021/jm00101a014

Source and publish data:

Journal of Medicinal Chemistry p. 4366 - 4372 (1992)

Update date:2022-08-05

Topics:

Authors:

Main, Alan J.

Bhagwat, Shripad S.

Boswell, Clay

Goldstein, Robert

Gude, Candido

et al. et al.

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Article abstract of DOI:10.1021/jm00101a014

A series of 8-<(arylsulfonyl)amino>octanoic acids substituted with a pyridinylalkyl group along the chain were synthesized and tested in vitro for their ability to both antagonize the binding of thromboxane A₂ to its receptors and to inhibit th

Full text of DOI:10.1021/jm00101a014

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