Thromboxane Receptor Antagonism Combined with Thromboxane Synthase Inhibition. 3. Pyridinylalkyl-Substituted 8-octanoic Acids

DOI: 10.1021/jm00101a014

Source and publish data:

Journal of Medicinal Chemistry p. 4366 - 4372 (1992)

Update date:2022-08-05

Topics:

Authors:

Main, Alan J.

Bhagwat, Shripad S.

Boswell, Clay

Goldstein, Robert

Gude, Candido

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00101a014

A series of 8-<(arylsulfonyl)amino>octanoic acids substituted with a pyridinylalkyl group along the chain were synthesized and tested in vitro for their ability to both antagonize the binding of thromboxane A₂ to its receptors and to inhibit th

Full text of DOI:10.1021/jm00101a014

Products guided by the article

Product name:methyl 8-<<(4-chlorophenyl)sulfonyl>amino>-8-(3-pyridinyl)octanoate

Cas No:144002-13-1

R&D Labs maybe for 144002-13-1

CHEM PLUS

Contact:0027-717-456976

Address:2ND FLOOR, 325 VAUSE ROAD, OVERPORT, 4001, SOUTH AFRICA
ANGCHEN BRIGHTCHEM CO., LTD

website:http://www.angchenchem.com

Contact:+86-510-88302099 82327577

Address:Rm. 404/405, Floor 4th, No. 983 FengXiang Road, Wuxi, China
Tianjin Tongde Biological Technology Co., Ltd.

Contact:86-22-23309138

Address:Room 402, bulidingE3 Detection certification park, XiQingDistrict, Tianjin City
Improve Medical Technology(Nanxiong) Co., Ltd

Contact:86-751-3836997

Address:No.33, Pingan First Road, Fine Chemical Industry Base, Nanxiong City, Shaoguan, Guangdong, China
Qingzhou Baibang import and export co.,Ltd

Contact:+86-536-3265899

Address:No.338, Tuoshan Road

Relevant to this article

Synthesis of a Fully Functionalized CD Ring System of Taxol

Doi:10.1039/c39920001118
(1992)
Structural optimization, biological evaluation, and application of peptidomimetic prostate specific antigen inhibitors

Doi:10.1021/jm301718c
(2013)
A closer look at the bromine-lithium exchange with tert-butyllithium in an aryl sulfonamide synthesis

Doi:10.1021/ol4010454
(2013)
Diphenyldiaza-18-krone-6-bis-pyrazoliden-acetonitril, ein neuer Chromoionophor Synthesen mit Nitrilen, 90.Mitt.

Doi:10.1007/BF00816852
(1992)
Doi:10.1016/S0020-1693(00)92348-X
(1992)
Organometallic calcium and strontium borohydrides as initiators for the polymerization of ε-caprolactone and l-lactide: Combined experimental and computational investigations

Doi:10.1039/c3dt00037k
(2013)

Article Doi