Selective Type IV Phosphodiesterase Inhibitors as Antiasthmatic Agents. The Syntheses and Biological Activities of 3-(Cyclopentyloxy)-4-methoxybenzamides and Analogues

DOI: 10.1021/jm00037a021

Source and publish data:

Journal of Medicinal Chemistry p. 1696 - 1703 (1994)

Update date:2022-08-02

Topics:

Authors:

Ashton, Michael J.

Cook, David C.

Fenton, Garry

Karlsson, Jan-Anders

Palfreyman, Malcolm N.

et al. et al.

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Article abstract of DOI:10.1021/jm00037a021

The syntheses and biological activities of a number of benzamide derivatives, designed from rolipram, which are selective inhibitors of cyclic AMP-specific phosphodiesterase (PDE IV), are described.The effects of changes to the alkoxy groups, amide linkag

Full text of DOI:10.1021/jm00037a021

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