Enantioselective catalytic borane reductions of achiral ketones: Synthesis and application of new catalysts prepared from (S)-tert-leucine and (S)-azetidinecarboxylic acid

Article abstract of DOI:10.1080/00397919208019066

Enantiocontrolled reduction of prochiral ketones with borane in the presence of homochiral amino alcohols 1-3 as enantioselective catalysts afforded the corresponding secondary alcohols in moderate to high (69 to >99%) optical yields.

Full text of DOI:10.1080/00397919208019066

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Synthetic Communications: An
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Enantioselective Catalytic
Borane Reductions of Achiral
Ketones: Synthesis and
Application Of New Catalysts
Prepared from (S)-Tert-Leucine
and (S)-Azetidinecarboxylic
Acid
W. Behnen a , Ch. Dauelsberg a , S. Wallbaum a & J.
Martens a
a Fachbereich Chemie , Universität Oldenburg ,
Ammerländer Heerstraß 114—118, D-2900,
Oldenburg i. O., Germany
Published online: 24 Sep 2006.
To cite this article: W. Behnen , Ch. Dauelsberg , S. Wallbaum & J. Martens
(1992) Enantioselective Catalytic Borane Reductions of Achiral Ketones: Synthesis
and Application Of New Catalysts Prepared from (S)-Tert-Leucine and (S)-
Azetidinecarboxylic Acid, Synthetic Communications: An International Journal
for Rapid Communication of Synthetic Organic Chemistry, 22:15, 2143-2153, DOI:
10.1080/00397919208019066
To link to this article: http://dx.doi.org/10.1080/00397919208019066

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