Synthesis and Antiviral Activity of Deoxy Analogs of 1--6-(phenylthio)thymine (HEPT) as Potent and Selective Anti-HIV-1 Agents

DOI: 10.1021/jm00103a009

Source and publish data:

Journal of Medicinal Chemistry p. 4713 - 4719 (1992)

Update date:2022-09-26

Topics:

Authors:

Tanaka, Hiromichi

Takashima, Hideaki

Ubasawa, Masaru

Sekiya, Kouichi

Nitta, Issei

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00103a009

The effect of substitution in the acyclic structure of 1-<(2-hydroxyethoxy)methyl>-6-(phenylthio)thymine (HEPT) on anti-HIV-1 activity was investigated by synthesizing a series of deoxy analogs and related compounds.Preparation of 1-<(2-alkyloxyethoxy)met

Full text of DOI:10.1021/jm00103a009

Products guided by the article

Product name:2,4(1H,3H)-Pyrimidinedione, 1,3,5-trimethyl-6-(phenylthio)-

Cas No:144410-28-6

R&D Labs maybe for 144410-28-6

Maithili Life Sciences

Contact:+91 9963263336

Address:Plot#146A, IDA Mallapur, Hyderabad - 500072
Zhejiang Sucon Silicone Co.,Ltd

Contact:+86-575-88046692

Address:Qisheng Rd., Paojiang Industrial Zone, Shaoxing, Zhejiang, China.
Weifang Adde Economic And Trade Co.,LTD.

Contact:86-536-8885548

Address:Room 1402,Wanda Plaza B Block,No.958,Yuanfei Road,Kuiwen District
Hefei EnliPharma Tecnology Co.,Ltd

Contact:0086-551-66399836

Address:Qing Cheng ShuiXiang Building 805, Mengcheng North Road , ShuangFeng Economic Development Zone Anhui HeFei
Hangzhou Hysen Pharma co.,Ltd.

website:http://www.hysenpharma.cn/

Contact:0086-571-88298791

Address:#701,Gudun Road Hangzhou

Relevant to this article

Ultrathin reduced graphene oxide films as transparent top-contacts for light switchable solid-state molecular junctions

Doi:10.1002/adma.201300607
(2013)
Oligonucleotide analogues with integrated bases and backbone. Part 30: Synthesis and association of a self-complementary thiomethylene-linked octanucleoside

Doi:10.1002/hlca.201300043
(2013)
Synthesis and characterization of 1,4-dihydropyridine-substituted metallophthalocyanines

Doi:10.1016/j.mencom.2013.07.016
(2013)
Highly active nano-MgO catalyzed, mild, and efficient synthesis of amidines via electrophilic activation of amides

Doi:10.1016/j.tetlet.2013.05.096
(2013)
Azaphthalocyanines: Red fluorescent probes for cations

Doi:10.1002/chem.201300079
(2013)
Synthesis, characterization and DNA interaction of new copper(II) complexes of Schiff base-aroylhydrazones bearing naphthalene ring

Doi:10.1016/j.jphotobiol.2013.02.014
(2013)

Article Doi