Enzyme-Catalysed Hydrolysis of N-Benzyloxycarbonyl-cis-2,6-(acetoxymethyl)piperidine. A Facile Route to Optically Active Piperidines

DOI: 10.1016/S0957-4166(00)86034-6

Source and publish data:

Tetrahedron Asymmetry p. 1021 - 1024 (1992)

Update date:2022-07-30

Topics:

Authors:

Chenevert, Robert

Dickman, Michael

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0957-4166(00)86034-6

We report the first enzymatic asymmetrization of a piperidine system.Hydrolysis of N-benzyloxycarbonyl-cis-2,6-(acetoxymethyl)piperidine in the presence of Aspergillus niger lipase gave the corresponding 2R, 6S mono-acetate in good chemical yield and very

Full text of DOI:10.1016/S0957-4166(00)86034-6

Products guided by the article

Product name:(2R,6S)-2-Acetoxymethyl-6-(tert-butyl-dimethyl-silanyloxymethyl)-piperidine-1-carboxylic acid benzyl ester

Cas No:144433-73-8

R&D Labs maybe for 144433-73-8

shanghai tuomiao chemicial co.,ltd.

website:https://www.tuomiaochem.com/

Contact:021 - 59853336

Address:shanghai
Jinan Hongfangde Pharmatech Co.LTD

Contact:0531-88870908

Address:F Bldg,750#,Shunhua Rd,New&High-tech Zone,Jinan,Shandong,China 250101
ZHEJIANG NHU COMPANY LTD.

Contact:86-575-86132822，86-575-86085355

Address:No.418 Dadao West Road,Qixing Street,Xinchang, Zhejiang Province, China.
zhejiang huangyan wanfeng pharm chem co.ltd

Contact:+86-576- 84160728

Address:No. 5 Dazha Road, Economic,Development Zone(JiangKou), Zhejiang, China
ShenZhen InnoSyn Biotech Co.,Ltd

website:http://www.innosyns.com

Contact:+86-755-28351685

Address:Floor 5 & 6, Building A1, HAIKEXING Strategic Innovative Industrial Park, 16 BaoShan Road, PingShan District

Relevant to this article

Iron-catalyzed ferrocenylmethanol OH substitution by S, N, P, and C nucleophiles

Doi:10.1002/ejic.201300239
(2013)
Synthesis and Biological Evaluation of Calothrixins B and their Deoxygenated Analogues

Doi:10.1021/acs.jmedchem.7b01797
(2018)
Enantioselective Addition of Azlactones to Ethylene Sulfonyl Fluoride via Dual Catalysis

Doi:10.1021/acs.orglett.1c01193
(2021)
RING-CHAIN ISOMERISM OF 1,3,3-TRIMETHYL-2-FORMYLMETHYLENEINDOLINE (FISCHER ALDEHYDE) OXIME AND ASSOCIATED REACTIONS

Doi:10.1007/BF00473933
(1992)
Design of Gut-Restricted Thiazolidine Agonists of G Protein-Coupled Bile Acid Receptor 1 (GPBAR1, TGR5)

Doi:10.1021/acs.jmedchem.8b00308
(2018)
Synthesis of (Z)-1-(1,3-diphenyl-1 H -pyrazol-4-yl)-3-(phenylamino)prop-2-en-1-one derivatives as potential anticancer and apoptosis inducing agents

Doi:10.1016/j.ejmech.2016.03.051
(2016)

Article Doi