Enzyme-Catalysed Hydrolysis of N-Benzyloxycarbonyl-cis-2,6-(acetoxymethyl)piperidine. A Facile Route to Optically Active Piperidines

DOI: 10.1016/S0957-4166(00)86034-6

Source and publish data:

Tetrahedron Asymmetry p. 1021 - 1024 (1992)

Update date:2022-07-30

Topics:

Authors:

Chenevert, Robert

Dickman, Michael

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0957-4166(00)86034-6

We report the first enzymatic asymmetrization of a piperidine system.Hydrolysis of N-benzyloxycarbonyl-cis-2,6-(acetoxymethyl)piperidine in the presence of Aspergillus niger lipase gave the corresponding 2R, 6S mono-acetate in good chemical yield and very

Full text of DOI:10.1016/S0957-4166(00)86034-6

Products guided by the article

Product name:(2R,6S)-2-Acetoxymethyl-6-(tert-butyl-dimethyl-silanyloxymethyl)-piperidine-1-carboxylic acid benzyl ester

Cas No:144433-73-8

R&D Labs maybe for 144433-73-8

RongCheng K&S Chemical Co.,Ltd

Contact:0631-7336369

Address:rongcheng ,shandong province china
Shijiazhuang City Xiehe Pharmaceutical Co., Ltd

Contact:+86-311-80817929

Address:Shangzhuang,Shijiazhuang,China
Wuhan Pengo Technology.,Ltd.

Contact:+86-27-67841589

Address:Add: 999 Gaoxin Road, Donghu New Technology Development Zone, Wuhan City, Hubei, China
Neworld Chemical Co., Ltd Shanghai(expird)

Contact:+86-21-62202658

Address:11F, Blvd 2, No. 1969 PuXing Rd, Shanghai
Beijing Ribio Biotech Co.,Ltd

Contact:86-10-62664360

Address:Building 10,No.18 AnNingZhuang East Road, GuangHua Pioneer Park,HaiDian District, BeiJing China

Relevant to this article

Iron-catalyzed ferrocenylmethanol OH substitution by S, N, P, and C nucleophiles

Doi:10.1002/ejic.201300239
(2013)
Synthesis and Biological Evaluation of Calothrixins B and their Deoxygenated Analogues

Doi:10.1021/acs.jmedchem.7b01797
(2018)
Enantioselective Addition of Azlactones to Ethylene Sulfonyl Fluoride via Dual Catalysis

Doi:10.1021/acs.orglett.1c01193
(2021)
RING-CHAIN ISOMERISM OF 1,3,3-TRIMETHYL-2-FORMYLMETHYLENEINDOLINE (FISCHER ALDEHYDE) OXIME AND ASSOCIATED REACTIONS

Doi:10.1007/BF00473933
(1992)
Design of Gut-Restricted Thiazolidine Agonists of G Protein-Coupled Bile Acid Receptor 1 (GPBAR1, TGR5)

Doi:10.1021/acs.jmedchem.8b00308
(2018)
Synthesis of (Z)-1-(1,3-diphenyl-1 H -pyrazol-4-yl)-3-(phenylamino)prop-2-en-1-one derivatives as potential anticancer and apoptosis inducing agents

Doi:10.1016/j.ejmech.2016.03.051
(2016)

Article Doi