Tetrahedron p. 6317 - 6324 (1992)
Update date:2022-09-26
Topics:
Evidente, Antonio
Lanzetta, Rosa
Capasso, Renato
Vurro, Maurizio
Bottalico, Antonio
Two additional cytochalasins were isolated from liquid culture filtrates of Phoma exigua var. heteromorpha together with some already known cytochalasins.The two new metabolites, named cytochalasin U and V, represent the first natural occurrence of a 25,26-dioxa<16> and 25-oxa<15>cytochalasan, respectively, both bearing a formyl group on the macrocyclic ring.Cytochalasins U and V showed respectively significant and weak activity in the brine shrimp assay.
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